Membrane structure

Topic 1.3

Essential idea: The structure of biological membranes makes them fluid and dynamic.

Understandings

1.3.U1 Phospholipids form bilayers in water due to the amphipathic properties of phospholipid molecules.

Cell membrane stability

1.3.U2 Membrane proteins are diverse in terms of structure, position in the membrane and function.

Membrane Functions

1.3.U3 Cholesterol is a component of animal cell membranes.

Membrane Structure

The the figure below shows the structure of the plasma membrane including phospholipid bilayer, cholesterol, glycoproteins, and integral and peripheral proteins. The term plasma membrane, not the cell surface membrane, is used for the membrane surrounding the cytoplasm. Integral proteins are embedded in the phospholipid bilayer, whereas peripheral proteins are attached to a surface.

Membranes link Membrane animation
Structure of the plasma membrane

Applications

1.3.A1 Cholesterol in mammalian membranes reduces membrane fluidity and permeability to some solutes.

cholesterol and membrane fluidity

Skills

1.3.S1 Drawing of the fluid mosaic model

The the figure below shows the structure of the plasma membrane including phospholipid bilayer, cholesterol, glycoproteins, and integral and peripheral proteins. The term plasma membrane, not the cell surface membrane, is used for the membrane surrounding the cytoplasm. Integral proteins are embedded in the phospholipid bilayer, whereas peripheral proteins are attached to a surface.

Membranes link Membrane animation
Structure of the plasma membrane

1.3.S2 Analysis of evidence from electron microscopy that led to the proposal of the Daveson-Danielli model

Evidence for Davson-Danielli Model of the cell membrane

1.3.S3 Analysis of the falsification of the Davson-Danielli model that led to the Singer-Nicolson model.

Falsification of Davson-Danielli Model of the cell membrane
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